Hadatomo™ Photoacoustic Microscope WEL5100
Noninvasive, High Contrast Imaging of Blood Vessels to a Depth of 3mm
Evaluations of treatments for blood circulation disorders, as well as regenerative medicine therapies, currently rely on biopsies and animal experiments, but these methods have well-noted shortcomings. Advantest's new Hadatomo™ photoacoustic microscope addresses these drawbacks, offering researchers an unprecedented non-invasive process for analyzing blood vessels within the dermis. Utilizing a new imaging method that combines optical technology and ultrasound, the Hadatomo™ provides high-contrast images of blood vessels without the use of contrast agents. This new imaging technology is poised to contribute to further advances in regenerative medicine, dermatology, and plastic surgery.
Quasi-Real Time Imaging
Imaging of a 4 mm square area takes just 20 seconds.
High-speed imaging reduces patient stress and improves diagnosis times.
Proprietary Image Reconstruction Algorithms
Advantest's proprietary image reconstruction algorithms eliminate the need for an optical lens or acoustic lens, providing sharp, clear images regardless of the depth of the target area.
Setup is easy, requiring no calculations of target area depth.
No contrast agent required
The Hadatomo's compact frame makes it easy to move around.
Its flexible arm enables analysis of hard-to-reach areas.
|Pulse width||< 2 ns|
|Pulse energy||< 37 µJ/pulse (*1)|
|Measurement time settings||10/20/40/80 s|
|Max. measurement area||4 x 4 x 3(depth)mm|
|Scan step size||40 µm|
|Dimensions||Approx. 540 (W) × 545 (D) × 1,546 (H)|
|Weight||< 110 kg|
(*1): Pulse energy is constant, but the repetition frequency may differ depending on the
※ This product is categorized as a Scientific Instrument. It is not approved for use in diagnosis of diseases.
Existing ultrasound technology can noninvasively provide images of tissue structures by contrasting the relative hardness of constituent areas. However, it is inadequate to image areas within the dermis, where little hardness contrast exists.
Conversely, optical imaging tools such as microscopes cannot "see" even 1mm beneath the skin.
Photoacoustic imaging combines the propagation characteristics of ultrasound and the absorption characteristics of light into a next-generation hybrid imaging method that is used for R&D worldwide.
When pulses of light are irradiated into the target area, hemoglobin selectively absorbs their energy and returns ultrasonic waves to the surface of the skin, where they can be captured by sensors at the surface. Based on how long it takes for the waves to return, the depth of the target can be accurately measured and imaged.
3D image of a 4mm x 4mm x 3mm area of the palm, including the epidermis and dermis
3D images of 4mm x 4mm x 3mm areas of the fingertip, cheek, and foot, with cross-sections and subsurface views