Hadatomo™ Z Photoacoustic Microscope WEL5200
Noninvasive, High-Speed 3D Imaging of Blood Vessels in the Dermis
The HadatomoTM Ζ simultaneously images the oxygen saturation of blood vessels with two wavelengths of optical ultrasound, and images the skin texture, pores, and skin structures such as sebaceous glands with ultrasound.
Ultrasound that visualizes the skin structure based on the differences in tissue hardness, and optical ultrasound, which selectively images melanin and blood vessels based on their absorption characteristics, are integrated into one system.
The photoacoustic wave images and the ultrasonic wave images are measured simultaneously, with a minimum measurement time of 70 seconds (Range: 6 mm x 6 mm x 3 mm (depth)) and maximum time of 420 seconds (Range: 9 mm x 9 mm x 3 mm (depth)).
High-resolution images obtained with easy operation
An ultrasonic sensor developed especially for this system provides a high-resolution crosssection view. Focus points can be easily located by observing the cross-section.
Flexible design with easy operation and portability
The compactly designed system, equipped with a measurement unit mounted on a flexible arm, is installed on a system unit with caster wheels, easy to set up to measure various parts of the body.
Applying a small amount of water (acoustic coupling agent) to the measurement area is enough for measurement.
Non-invasive measurement is possible without any contrast agent.
Acquires data for 3-dimensional imaging
Measurement data are displayed as 2-dimensional cross-section images in real-time, and acquisition of 3-dimensional data images is possible. 3-dimensional image analysis is possible with customer-provided rendering software.
|Sampling frequency||500 MHz|
|Dimensions||Approx. 610 (W) × 730 (D) × 1,400 (H)|
|Weight||< 135 kg|
|Measurement area(x, y)||(1) 6 x 6 mm (2) 9 x 9 mm|
|Measurement depth(z)||3 mm|
|Scanning step||15 μm / 30 μm|
|Measurement time(15 μm)||(1) 210 s (2) 420 s|
|Measurement time(30 μm)||(1) 70 s (2) 140 s|
|Measurement area(x, )||6 mm|
|Measurement depth(z)||3 mm (designated signal acquisition range)|
|Image resolution||15 μm / 30 μm|
|Flame rate||1 fps|
|Wavelength||532 nm, 556 nm|
|Horizontal image resolution||15 μm|
|Axial image resolution||12 μm *1|
|Pulse energy||Below 16 μJ/pulse *2|
|Pulse width||10 ns以下|
|Repetition rate||1000 Hz *3|
|Horizontal image display||15 μm|
|Axial image display||12 μm *4|
|Transmission repetition rate||1000 Hz|
|Center frequency||60 MHz ± 20 %|
*1: Depending on ultrasound velocity
*2: Averaged value
*3: 1000 Hz per 1 wavelength
*4: Depending on ultrasound velocity
- Specifications may change without notification.
- This product is categorized as a Scientific Instrument. It is not approved for use in diagnosis of diseases.
Existing ultrasound technology can noninvasively provide images of tissue structures by contrasting the relative hardness of constituent areas. However, it is inadequate to image areas within the dermis, where little hardness contrast exists.
Conversely, optical imaging tools such as microscopes cannot "see" even 1mm beneath the skin.
Photoacoustic imaging combines the propagation characteristics of ultrasound and the absorption characteristics of light into a next-generation hybrid imaging method that is used for R&D worldwide.
When pulses of light are irradiated into the target area, hemoglobin selectively absorbs their energy and returns ultrasonic waves to the surface of the skin, where they can be captured by sensors at the surface. Based on how long it takes for the waves to return, the depth of the target can be accurately measured and imaged.
In vivo imaging at various parts of body